PET study of the cerebrometabolic effects on non-ionizing radiation from mobile phones

project team:

Albert Gjedde, Arne Møller, Paul Cumming, Christoffer Bailey, PET-Centre, Aarhus University

research institution
Center of Functionally Integrative Neuroscience (CFIN), PET-center, Aarhus University, Aarhus University Hospital

The present study aims to test the hypothesis that radiation from mobile phones affect the metabolism of the human brain. To test the claim of physiological or pathological activation, we will measure changes in glutamate concentration in living humans exposed to non-ionizing radiation from a cellular phone. A sham-condition with no radiation will act as a baseline. The order of the two conditions are blinded from both the subjects and the researchers.

PET protocol

Two groups of 12 healthy right-handed subjects aged 18-40 years are recruited for the study. A series of dynamic emission recordings with arterial sampling will be obtained from each subject using the ECAT Exact HR positron emission tomography at the Aarhus PET Centre. Subjects will undergo two scanning sessions with the ECAT HR (CTI/Siemens) whole body PET tomography operating in 3-D acquisition mode. One session with the mobile on, one with the mobile off. Each session will consist of a one hour C¹¹-NS1209 or FAZA scanning. Arterial blood samples for kinetic analysis will be collected.

T1-weighted MR head images will be obtained for each subject using a 3.0 T magnet. Summed emission recordings will be co-registered to the individual MR, which in turn be co-registered to a common MR of human brain in stereotaxic coordinates. Once the final transformation is calculated, parametric maps will be resampled into the common stereotaxic coordinates. The effects of treatment will be assessed by statistical parametric mapping (SMPM),in which the baseline and HF_EMR conditions will be contrasted.

Read abstract here ...

Dosimetry and analysis

project team:
O. Franek, Gert F. Pedersen, and J. Bach Andersen, Aalborg University

research institution:
Aalborg University

The mobile phone is a special version, ensuring that the person does not feel any difference from the on or off-situation from noise or heat generated by the phone. Based on the individual images SAR distributions have been calculated by an FDTD method, and being compared with the PET results.

No results as yet.


background research reading material publications links / contact
Danish Front page Det Strategiske Forskningsråd varetager forskningsprogrammet for ikke-ioniserende stråling. DSF’s bestyrelse udmønter ikke selv programmidler, og bestyrelsen har derfor nedsat en programkomite for ikke-ioniserende stråling bestående af fire anerkendte forskere. Der er afsat en samlet ramme på 30 mio. kr. til programmet. 15 mio. kr. blev uddelt i 2004, og 15 mio. kr. i 2005. Oplysninger om denne forskningsindsats – bl.a. omtale af de bevilgede projekter og forskernes oplæg på de afholdte åbne møder kan ses på DSF’s website på adressen: www.mobil.forsk.dk	PET study of the cerebrometabolic effects on non-ionizing radiation from mobile phones project team: Albert Gjedde, Arne Møller, Paul Cumming, Christoffer Bailey, PET-Centre, Aarhus University research institution Center of Functionally Integrative Neuroscience (CFIN), PET-center, Aarhus University, Aarhus University Hospital The present study aims to test the hypothesis that radiation from mobile phones affect the metabolism of the human brain. To test the claim of physiological or pathological activation, we will measure changes in glutamate concentration in living humans exposed to non-ionizing radiation from a cellular phone. A sham-condition with no radiation will act as a baseline. The order of the two conditions are blinded from both the subjects and the researchers. PET protocol Two groups of 12 healthy right-handed subjects aged 18-40 years are recruited for the study. A series of dynamic emission recordings with arterial sampling will be obtained from each subject using the ECAT Exact HR positron emission tomography at the Aarhus PET Centre. Subjects will undergo two scanning sessions with the ECAT HR (CTI/Siemens) whole body PET tomography operating in 3-D acquisition mode. One session with the mobile on, one with the mobile off. Each session will consist of a one hour C¹¹-NS1209 or FAZA scanning. Arterial blood samples for kinetic analysis will be collected. T1-weighted MR head images will be obtained for each subject using a 3.0 T magnet. Summed emission recordings will be co-registered to the individual MR, which in turn be co-registered to a common MR of human brain in stereotaxic coordinates. Once the final transformation is calculated, parametric maps will be resampled into the common stereotaxic coordinates. The effects of treatment will be assessed by statistical parametric mapping (SMPM),in which the baseline and HF_EMR conditions will be contrasted. Read abstract here ... Dosimetry and analysis project team: O. Franek, Gert F. Pedersen, and J. Bach Andersen, Aalborg University research institution: Aalborg University The mobile phone is a special version, ensuring that the person does not feel any difference from the on or off-situation from noise or heat generated by the phone. Based on the individual images SAR distributions have been calculated by an FDTD method, and being compared with the PET results. No results as yet.